Five figures of exostoses (tumours) on the left femur (thigh-bone) Engraving, 1749.

Figures 1-2 show the same example in two views, as do figures 4-5. Buffon became the "intendant" of the Jardin du Roi in 1736 and his Histoire naturelle has, as its base, his descriptive catalogue of the specimens of the "cabinet du roi". The third volume is concerned with the Natural History of Man. In the introduction to the work, he remarks that, even more than the most exact descriptions and the best illustrations, "Nothing contributes more to the advancement of Natural History, than the continual observation of the objects of which it comprises."