Trypanosomes and trypanosomiasis / by A. Laveran and F. Mesnil. : Translated and much enlarged by David Nabarro.

  • Laveran, Alphonse, 1849-1922.
Date:
1907
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Licence: In copyright

Credit: Trypanosomes and trypanosomiasis / by A. Laveran and F. Mesnil. : Translated and much enlarged by David Nabarro. Source: Wellcome Collection.

Provider: This material has been provided by London School of Hygiene & Tropical Medicine Library & Archives Service. The original may be consulted at London School of Hygiene & Tropical Medicine Library & Archives Service.

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    recent work of Schaudinn^ (loc. cit.), in which he regards the trypano- somes (and also the spirochsetes which, according to him, have fundamentally the same structure as trypanosomes)- as forming part of the developmental cycle of intracorpuscular hsematozoa (Hsemo- cytozoa). That view is based upon observations made upon two particular species of intracorpuscular parasites of the little owl {Athene nodua), which both complete their evolutionary cycle in the body of the common mosquito, Ctdex pipiens. In one species {Trypanosoma noctuce), the ookinete, or product of fertilization of a female by a male element, is transformed into a true trypanosome in the stomach of the mosquito. Fig. 5, copied from Schaudinn, shows the different stages of this transformation, which is accomplished in the following manner : The nucleus Fig. 5.—Transformation of an Ookinete of an Intracorpuscular Parasite into A Trypanosome (after Schaudinn). divides, by heteropolar mitosis, into A and a (Fig. 5, i) the central filament of the division spindle persisting. The part a divides in its turn into a and a (Fig. 5, 2), the new central filament again per- sisting. A is the principal nucleus, a the accessory nucleus or blepharoplast. Finally, a divides by mitosis, and gives rise to the whole of the flagellar apparatus (Fig. 5, j, ^, 5). The edge of the undulating membrane and the free fiagellum are the central filament of the spindle greatly elongated (which explains how it is the flagellum has a chromatin-staining reaction). The peripheral filaments of the division spindle also persist. ^ [A complete translation of this paper by Schaudinn appeared in the numbers of the Journ. Trap. Med., June i to November i, 1904. A very full analysis of it is given by Woodcock in his article in the Quart. Journ. Micr. Sc., v. 50. At the express wish of the authors, I have simply translated what they wrote in the original of their book, without making any alterations. I have, however, made some additions to the authors' original short rdsume.—Ed.] 2 [But Schaudinn afterwards abandoned this view that all spirochetes would be found to have fundamentally the same structure as trypanosomes.]