Contraceptive risk : the FDA, Depo-Provera, and the politics of experimental medicine / William Green.

  • Green, William, 1950-
Date:
[2017]
  • Books

About this work

Description

"Depo-Provera is known as an injectable hormonal birth control method, but few are familiar with its dark and complicated history. Depo-Provera was tested on women since the mid-1960s without their informed consent until it was FDA-approved in 1992, but never FDA-approved as chemical castration for male sex offenders. Contraceptive risk is William Green's landmark study of Depo-Provera. Based on a fascinating combination of archival materials and interviews, the book is framed as three interconnected stories told by Judith Weisz, who chaired the FDA's Public Board of Inquiry on Depo-Provera, a scientific court; by Anne MacMurdo who brought a products liability suit against Upjohn, the drug's manufacturer, for the deleterious side effects she suffered from the drug's use; and by Roger Gauntlett, an Upjohn heir who, when he was convicted of sexual assault, refused to take a dose of his family's own medicine as a probation condition. Together these three stories of Depo-Provera's convoluted fifty year odyssey call for a paradigm shift in pharmaceutical drug development. Contraceptive risk is a thoroughly researched and engrossing approach to the scientific, political and institutional forces involved in health law and policy, as well as the multifaceted politics of measuring risk"--Back cover.

Publication/Creation

New York : New York University Press, [2017]

Physical description

xiii, 322 pages ; 23 cm.

Bibliographic information

Includes bibliographical references (pages 239-303) and index.

Contents

Introduction : the odyssey of Depo-Provera -- The Grady Hospital study : the corruption of contraceptive research -- The twenty-five-year FDA approval controversy : cancer and the politics of acceptable risk -- Contraceptive chaos : unapproved use and Upjohn v. MacMurdo -- Marketing approval and litigation : osteoporosis and the realities of medical risk -- Chemical castration : the John Hopkins Clinic and People v. Gauntlett -- Conclusions : contraceptive drug risk failure, human dignity, and a duty to act.

Languages

Where to find it

  • LocationStatus
    History of Medicine
    TPU.6
    Open shelves

Permanent link

Identifiers

ISBN

  • 9781479876990
  • 1479876992
  • 9781479836987
  • 1479836982