Note on the influence of castration on the weight of the brain and spinal cord in the albino rat and on the percentage of water in them / Henry H. Donaldson and S. Hatai.

  • Donaldson, Henry Herbert, 1857-1938.
Date:
1911
Catalogue details

Licence: In copyright

Credit: Note on the influence of castration on the weight of the brain and spinal cord in the albino rat and on the percentage of water in them / Henry H. Donaldson and S. Hatai. Source: Wellcome Collection.

Provider: This material has been provided by The Royal College of Surgeons of England. The original may be consulted at The Royal College of Surgeons of England.

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    TABLE 1 Rats still increasing in body weight at time of killing LITTER BODY i BODY BRAIN CORD PER CENT WATER AGE WEIGHT 1 LENGTH WEIGHT WEIGHT BRAIN CORD DAYS Castrated v 227.6 194 1.9746 .6168 77.62 . 69.45 260 V 258.0 202 1.9434 .6728 77.36 68.37 260 X 156.6 163 1.7726 .4966 77.28 68.10 234 Average.. 214.1 186 1.8968 .5954 77.42 68.64 251 Controls III 272 194 2.0198 .6556 77.12 67.81 290 V 281 199 2.0910 .6364 77.01 67.94 260 V 268 198 2.0610 .6703 77.85 69.32 260 VI 303 205 2.0636 .6904 77.64 67.90 271 X 210.4 174 1.8354 .5494 77.16 68.51 234 Average.. 267.0 194 2.0141 .6404 77.36 68.29 363 As the data in table 1 stand, the controls show heavier brain and spinal cords than those castrated. This is not only true for the averages of the entire groups, but also for the averages of the litters, so far as they can be contrasted. To make the compari- son trustworthy, however, we have referred the values found to the series of standard values in the manner described by Donald- son (Tl) in the accompanying study on the influence of exercise on the weight of the central nervous system. When this is done, it is found that both groups are above the standard as follows: BRAIN SPINAL CORD Body length 194 mm. Body length 186 mm. Excess of observed values in controls... . Excess of observed values in castrated... per cent. 9.9 5.7 per cent. 18.5 11.6 1 )p(iCloneV in t.lio cn.strn.fpr] (rrnnn 4.2 6.9