The pathology and treatment of phlegmasia dolens / by F. W. Mackenzie.

  • MacKenzie, Frederick William.
Date:
1862
Catalogue details

Licence: Public Domain Mark

Credit: The pathology and treatment of phlegmasia dolens / by F. W. Mackenzie. Source: Wellcome Collection.

Provider: This material has been provided by Royal College of Physicians, London. The original may be consulted at Royal College of Physicians, London.

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    mit that a more perfect specimen of extensive inflammation and obstruction of the crural veins cannot be found in the necroscopical history of phlegmasia dolens than that which was presented by the dissection from which it is copied, and which it so accurately represents. The history of the case is the following. Expeeiment. Tlie right femoral vein of a dog was ligatured on the 16th of June, 1852, and the effects of the operation were carefully noted for several days. In twenty-four hours there was some little oedema of the limb, but it was not painful or tender, and the dog moved it without difficulty. In forty-eight hours the oedema was nearly gone. In seventy-two hours there was none perceptible, and the limb appeared to be perfectly natural. The left femoral vein was now ligatured, and above the ligature half a drachm of lactic acid diluted with ten drachms and a half of tepid water was injected towards the heart. In twenty- four hours the corresponding extremity was greatly swollen throughout, its temperature was raised, it was painful on pres- sure, and the dog moved it with difficulty. In forty-eight hours its general condition was the same, the swelling was still considerable, the limb was tender on pressure, and the dog still moved it with difficulty. It was now killed, and the parts examined. Dissection. The left posterior extremity was generally swollen. The subcutaneous and intermuscular cellular tissue was morbidly vascular and infiltrated, and the muscles them- selves were in places swollen and congested. The iliac veins of this side were obstructed with a firm coagulum, which extended somewhat into the cava, whilst the femoral and all the princi- ]oal veins of this extremity were found similarly obstructed. On opening these vessels it was found that the external and com- mon iliac veins were filled with a firm coagulum, which was