Round celled sarcoma of the anterior mediastinum : extensive metastases, including the brain, both choroid coats, oculo-motor and optic nerves, and external ocular muscles / by Arthur V. Meigs and G. E. de Schweinitz.

  • Meigs, Arthur V. (Arthur Vincent), 1850-1912.
Date:
[1894]
Catalogue details

Licence: Public Domain Mark

Credit: Round celled sarcoma of the anterior mediastinum : extensive metastases, including the brain, both choroid coats, oculo-motor and optic nerves, and external ocular muscles / by Arthur V. Meigs and G. E. de Schweinitz. Source: Wellcome Collection.

Provider: This material has been provided by UCL Library Services. The original may be consulted at UCL (University College London)

    9/16 (page 9)
    the nerves supplying the inferior rectus, contained within the body of the muscle, although themselves not infiltrated, are liberally surrounded with sarcoma cells, which infiltrate their external connective-tissue investments. Fig.4. Section of inferior rectus showing sarcoma cells between muscle-fibres. Bloodvessels. The following bloodvessels are evident in the section : the supra-orbital, ophthalmic, and ciUary arteries and branches of the ophthalmic veins. The coats of these vessels are free from infiltration, except in the case of the ciliary branches lying between the optic nerve and the patch of infiltration in the inferior rectus, and even in these the sarcoma cells lie rather in the loose fibro-fatty tissue adjacent to the vessels than in coats of the artery itself, although in some instances small foci may be seen in the adventitious tunic. In the small vessels supplying the inferior rectus muscle this character of infiltration (i. e., within the adventitious coat) is more con- spicuous. Transverse secti07i of a portion of the contents of the right orbit. As the contents were fragmentary, the relation of the various constituents to each other, and consequently their identification, is imperfect. Muscles. The following muscles appear to be included: superior rectus, levator palpebrae superioris, a fragment of the superior oblique, and the internal (or inferior) rectus. These structures have escaped the sarcomatous infiltration, with the exception of the last-named muscle, which contains two patches of diseased tissue exactly similar to the one described in the inferior rectus of the left orbit. The branches of the oculo-motor nerve supplying this muscle are not only surrounded by sarcoma cells, but the individual fibres have been separated by the elements of the new growth precisely as the same process has occurred in the main stems of both third nerves.